Nature Chemistry
Nanoscale iron catalysts for scalable and selective deuteration of (hetero)arenes
We have developed a general methodology for heterogeneous iron-catalysed deuteration reactions. The catalytic system is effective for selective deuteration of anilines, indoles, phenols, and other heterocyclic compounds including late-stage labelling of natural products as well as bioactive molecules and can be readily used for the preparation of deuterated compounds on kg-scale.
Developing a hybrid process for the production of olefins from glucose using cellular and heterogeneous catalysis
In a collaboration with Paul Dauenhauer's group at the University of Minnesota through the NSF Center for Sustainable Polymers, we have developed a new strategy to deoxygenate hydrocarbons produced by microbial fermentation of glucose using simple Lewis acid catalysis.
A protein hindered from folding by its parent ribosome
Cassaignau and colleagues use NMR to reveal how a dynamic elongating nascent polypeptide interacts with the ribosome to modulate its folding (https://www.nature.com/articles/s41557-021-00796-x)
