We report a ternary MOF-based photocatalyst Pt@NH2-UiO-66/CdS with a spatially separated structure for the hole-trap transfer pathway in the photocatalytic hydrogen evolution reaction processes.

An efficient synthesis of aryldifluoromethyl aryl ethers was established via nickel-catalyzed aryloxydifluoromethylation. Using this protocol, difluoromethylated PD-1/PD-L1 immune checkpoint inhibitors were comveniently achieved with enhanced antitumor efficacy over the non-fluoro congeners.