Sacrificial Template Replication: Fabrication of arbitrary three-dimensional suspended hollow microstructures in transparent fused silica glass
Glass is a versatile material, but it is very difficult to structure. Specifically, the generation of hollow channel structures as required, e.g., for synthesis-on-a-chip applications, has been very difficult to achieve. Here we demonstrate a novel approach to glass structuring enabling an entirely new real of complexity in terms of structure geometries and design of freedom.
Pharmacophore-Directed Retrosynthesis: Intertwining Natural Product Total Synthesis and Structure-Activity Relationship Studies