Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows.
Tuning organic crystal chirality by the molar masses of tailored polymeric additives
We introduced a feasible way to fabricate enantiopure chiral crystal aggregates directly from their racemic solution and their chirality can be tuned by the molar masses of polymeric additives.
Hydroxylamine-Mediated C-C Amination via an Aza-Hock Rearrangement
We report the aza-Hock rearrangement of benzyl alcohols with arylsulfonyl hydroxylamines (ArSO2ONHR) in fluorinated alcohols (HFIP or TFE), delivering anilines in good to excellent yields.
Developing a hybrid process for the production of olefins from glucose using cellular and heterogeneous catalysis
In a collaboration with Paul Dauenhauer's group at the University of Minnesota through the NSF Center for Sustainable Polymers, we have developed a new strategy to deoxygenate hydrocarbons produced by microbial fermentation of glucose using simple Lewis acid catalysis.
A protein hindered from folding by its parent ribosome
Cassaignau and colleagues use NMR to reveal how a dynamic elongating nascent polypeptide interacts with the ribosome to modulate its folding (https://www.nature.com/articles/s41557-021-00796-x)