The chemical and structural complexity of crystalline metal-organic frameworks (MOFs), which are network architectures formed from linked inorganic and organic components, presents great challenges for their characterization. Recently, one family of MOFs have been shown to melt (without decomposition), and form glasses upon quenching of the resultant liquids. The arrangements of atoms in these liquids and glasses are, by their nature, highly disordered and lack a unit cell. They are thus even more demanding to characterize than their crystalline counterparts.