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Richard Mathies

Professor of Chemistry, University of California, Berkeley

About Richard Mathies

Photochemistry of Vision Biophysical and bioanalytical chemistry time resolved spectroscopy microfluidics astrobiology

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510 642-4192
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On the Critical Role of Vibrational Phase in the Photochemistry of Vision

Vibronic coupling is a critical component of most mechanisms invoking quantum effects in biological processes. However, it is not clear how properties associated with vibrational coherence such as phase and coupling of atomic motion impact the efficiency of light-induced processes. Here, we show that deuteration of the H11-C11=C12-H12 double-bond of the 11-cis retinal chromophore in the visual pigment rhodopsin significantly and unexpectedly alters the photoisomerization yield. These results reveal a new vibrational phase-dependent isotope effect.
Go to the profile of Richard Mathies
Mar 21, 2018